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Lesson 7 of9
In Progress

Disease State Considerations

Jimmy October 25, 2021

  • Elderly 🡪 Low-dose SGA d/t minimal QTc effects
    • Caution – benzodiazepines
      • Prolonged sedation, paradoxical agitation, deliriogenic
    • Caution – first-generation antipsychotic
      • With anticholinergic, can exacerbate constipation/urinary retention and worsen agitation 
  • Dementia 🡪 SGA or benzodiazepine
    • Caution – first-generation antipsychotic
      • If dementia related to Parkinson’s disease, can worsen symptoms
  • Alcohol 🡪 FGA or SGA
    • Caution – benzodiazepines
      • Concurrent respiratory depression
  • Psychiatric illness 🡪 SGA
    • Addresses psychosis and underlying disease state
  • Drug intoxication/withdrawal 🡪 benzodiazepine or FGA/SGA
    • Differentiate between agitation d/t EtOH intoxication or withdrawal