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  • HCV-antibody testing
  • HCV RNA polymerase chain reaction (PCR)
  • Quantitative HCV-RNA prior to treatment initiation to document baseline level of viremia
  • HCV genotype
  • Cirrhosis assessment via liver fibrosis (Fibroscan or Fibrotest)
  • Prior treatment history
  • HCV-antibody testing likely to be positive once exposed; HCV RNA by PCR helps determine if current (active) infection
  • Cirrhosis assessment via liver fibrosis (Fibroscan or Fibrotest)
  • If F4, calculate Child-Pugh Score to determine cirrhotic state
    • Compensated or decompensated