Guidelines
- AHA/ASA Guidelines for the Early Management of Acute Ischemic Stroke
Primary Literature
- Tissue plasminogen activator for acute ischemic stroke (NINDS)
- Hacke W, et al. “Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke” (ECASS III)
- Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)
Review Article
- Emergency Neurological Life Support: Acute Ischemic Stroke
Podcast & Blogs
First10 EM: Thrombolytics for stroke: The evidence
EM Crit: Podcast 116 – the tPA for Ischemic Stroke Debate